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Catalogue Number:A188738
Chemical Name:9-O-Acetyl Paliperidone
Synonyms:9-(Acetyloxy)-3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one 1,2-benzisoxazole Derivative;
CAS Number:130049-87-5
Molecular Formula:C₂₅H₂₉FN₄O₄
Molecular Weight:468.52
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:9-O-Acetyl Paliperidone can be synthesized in one step from Paliperidone (P141000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
References:Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),
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