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Catalogue Number:A189223
Chemical Name:(S)-2-(Acetylthio)-propanoic Acid
CAS Number:167466-66-2
Molecular Formula:C₅H₈O₃S
Appearance:Yellow Oil
Molecular Weight:148.18
Solubility:Methanol
Category:Standards; Miscellaneous;
Applications:(S)-2-(Acetylthio)-propanoic Acid is an intermediate in synthesizing (R)-(+)-Thiolactomycin (T350880). It is a natural product inhibitor of b-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).
References:Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)
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