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CAS:1410809-36-7|ACHN 975

发布时间:2024-06-05 分享至:

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Catalogue Number:A189820
Chemical Name:ACHN 975
Synonyms:N-[(1S)-2-Amino-1-[(hydroxyamino)carbonyl]-2-methylpropyl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]-1,3-butadiyn-1-yl]-benzamide
CAS Number:1410809-36-7
Molecular Formula:C₂₀H₂₃N₃O₄
Molecular Weight:369.41
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:ACHN 975 inhibits LpxC, an essential enzyme in the Gram-negative lipid A biosynthetic pathway, and is the first LpxC inhibitor to enter human clinical trials.
References:Trend, R., et al.: PCT Int. Appl., WO 2013039947 A1 20130321 (2013)
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