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CAS:42228-92-2|Acivicin

发布时间:2024-06-05 分享至:

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Catalogue Number:A190150
Chemical Name:Acivicin
Synonyms:(αS,5S)-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic Acid; [S-(R*,R*)]-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic Acid; AT 125; Antibiotic AT 125; NSC 163501; U 42126; (+)-Acivicin
CAS Number:42228-92-2
Molecular Formula:C₅H₇ClN₂O₃
Appearance:White to Off-White Solid
Melting Point:>177°C (dec.)
Molecular Weight:178.57
Storage:4°C
Solubility:Dichloromethane (Slightly, Heated), Water (Slightly, Sonicated)
Stability
Hygroscopic
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:Azaserine and Acivicin are classical and irreversible inhibitors of γ-Glutamyltranspeptidase (GGT). Acivicin is a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells.
References:Hanigan, M., et al.: Biochemistry, 32, 6302 (1993);
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