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Catalogue Number:A190230
Chemical Name:Acolbifene
Synonyms:(2S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol;(S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; Acolbifene; EM 652; Sch 57068
CAS Number:182167-02-8
Molecular Formula:C₂₉H₃₁NO₄
Molecular Weight:457.56
Category:Research Tools;
Applications:Acolbifene is a selective estrogen receptor modulator (SERM) acting as pure antiestrogen. Acolbifene is also the orally active antiestrogen which is the most potent of the known antiestrogens and exerts pure antiestrogenic activity in the mammary gland and endometrium.
References:Gauthier, S., et al.: J. Enzyme Inhibition Med. Chem., 20, 165 (2005); Tremblay, G., et al.: Cancer Res., 58, 877 (1998)
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