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Catalogue Number:A190265
Chemical Name:Acotiamide Methyl Ether
Synonyms:N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2,4,5-trimethoxybenzoyl)amino]-4-thiazolecarboxamide
Impurity:Acotiamide EP Impurity A
CAS Number:185103-80-4
Molecular Formula:C₂₂H₃₂N₄O₅S
Molecular Weight:464.58
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Acotiamide Methyl Ether is a metabolite of Acotiamide (A190260, HCl); an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
References:Masanao, K., et. al.: Eur. J. Pharmacol., 666, 218 (2011); Matsunaga, Y., et. al.: J. Pharmacol. Exp. Ther., 336, 791 (2011)
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