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Catalogue Number:A191305
Chemical Name:N6-Acryloyl Ibrutinib
Synonyms:1-[(3R)-3-[4-(Acyloyl)amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one; 1-[(3R)-3-[4-(1-Oxo-2-propen-1-yl)amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one;
CAS Number:2031255-27-1
Molecular Formula:C₂₈H₂₆N₆O₃
Molecular Weight:494.54
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N6-Acryloyl Ibrutinib is an impurity of Ibrutinib (I124970), which is a immunotherapeutic drug used to target B cell receptor signaling and can possibly inhibit Wnt signaling.
References:Li, P., et al.: Mol. Med. Rep., 13, 4934 (2016); Wu, J., et al.: J. Hematol. Onco., 8, 104 (2015)
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