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Catalogue Number:A191815
Chemical Name:[4-​[[(2-​Aminoethyl)​thio]​methyl]​-​2-​thiazolyl]​-guanidine Dihydrochloride
Synonyms:1-(4-(((2-Aminoethyl)thio)methyl)thiazol-2-yl)guanidine Dihydrochloride
CAS Number:71916-64-8
Alternate CAS #
71916-66-0
Molecular Formula:C₇H₁₃N₅S₂ • 2(HCl)
Molecular Weight:231.34 + 2(36.46)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:[4-​[[(2-​aminoethyl)​thio]​methyl]​-​2-​thiazolyl]​-guanidine Dihydrochloride is an intermediate in the synthesis of Ebrotidine (E320550).Ebrotidine is a H2 receptor antagonist that has shown gastroprotective properties against gastric mucosal damange.
References:Andrade, R.J., et al.: Hepatol., 44, 1581 (2006); Wajima, T., et al.: J. Pharma. Sci., 92, 2427 (2003); Sentellas, S.. et al.: J. Chroma., 976, 221 (2002);
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