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Catalogue Number:A192200
Chemical Name:trans-ACUB
Synonyms:4-[[Trans-4-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]cyclohexyl]oxy]-benzoic Acid;
CAS Number:885012-33-9
Molecular Formula:C₂₄H₃₂N₂O₄
Molecular Weight:412.52
Category:Research Tools;
Applications:trans-ACUB is a potent inhibitor of soluble epoxide hydrolase (sEH) which is known to convert epoxides to their corresponding diols. Inhibitors of sEH act as anti-inflammatory, anti-hypertensive and cardioprotective agents.
References:Shihadih, D. et al.: Bioorg. Med. Chem. Lett., 25, 276 (2015);
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