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Catalogue Number:A194335
Chemical Name:Acyclovir Impurity O (N-Hydroxymethyl Acyclovir), Technical Grade
Synonyms:9-((2-Hydroxyethoxy)methyl)-2-((hydroxymethyl)amino)-1H-purin-6(9H)-one
CAS Number:2190509-40-9
Molecular Formula:C₉H₁₃N₅O₄
Appearance:White to Off-White Solid
Melting Point:>250oC (dec.)
Molecular Weight:255.24
Storage:-20°C
Solubility:Aqueous Base (Slightly), DMSO (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:N-Hydroxymethyl Acyclovir is an impurity of Acyclovir (A192400), an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral.
References:Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979), Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988), Whitley, R. J., et al.: N. Engl. J. Med., 327, 782 (1992)
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