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Catalogue Number:A208200
Chemical Name:Adamantoic Acid
Synonyms:1-Adamantanecarboxylic Acid; 1-Adamantane-1-carboxylic Acid; 1-Adamantylcarboxylic Acid; 1-Carboxyadamantane; NSC 94182; Tricyclo[3.3.1.13,7]decane-1-carboxylic Acid
CAS Number:828-51-3
Molecular Formula:C₁₁H₁₆O₂
Appearance:White to Off-White Solid
Melting Point:173-174°C
Molecular Weight:180.24
Storage:4°C
Solubility:Chloroform, Methanol (Slightly)
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Adamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation.
References:Baures, P. et al.: Bioorg. Med. Chem., 6, 1389 (1998); Christopherson, R. et al.: Biochem., 24, 1116 (1985); Chao, Herbert S. & Berchtold, G.: Biochem., 21, 2778 (1982)
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