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Catalogue Number:A208700
Chemical Name:(S)-Boc-adamantylglycine
Synonyms:(αS)​-α-​[[(1,​1-​Dimethylethoxy)​carbonyl]​amino]​-​tricyclo[3.3.1.13,​7]​decane-​1-​acetic Acid
CAS Number:361441-97-6
Molecular Formula:C₁₇H₂₇NO₄
Appearance:White to Off-White Solid
Melting Point:250-254°C
Molecular Weight:309.4
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly)
Category:Building Blocks; Chiral Molecules; Miscellaneous;
Applications:(S)-Boc-adamantylglycine is used to prepare saxagliptin (BMS-477118) as highly potent and long-acting and orally active dipeptidyl peptidase IV inhibitor for treatment of type 2 diabetes.
References:Augeri, D., et al.: J. Med. Chem., 48, 5025 (2005)
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