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CAS:110143-10-7|6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine

发布时间:2024-06-05 分享至:

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Catalogue Number:A212325
Chemical Name:6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine
Synonyms:Lodenosine; 9-(2,3-Dideoxy-2-fluoro-β-D-threo-pentofuranosyl)-9H-purin-6-amine; 2'-β-Fluoro-2',3'-dideoxyadenosine; 9-(2,3-Dideoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine; F-ddA; Lodensine; NSC 613792;
CAS Number:110143-10-7
Molecular Formula:C₁₀H₁₂FN₅O₂
Molecular Weight:253.24
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Anti-virals/Anti-retrovirals;
Applications:6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine is the experimental HIV reverse transcriptase inhibitor. It was designed as a chemically and enzymatically stable anti-AIDS drug. An antiviral agent.
References:Cambiano, V., et al.: AIDS, 24, 1153 (2010); De Clercq, E., et al.: Antivir. Chem. Chemother., 19, 75 (2008)
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