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CAS:2230820-11-6|AZD-​7648

发布时间:2024-06-05 分享至:

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Catalogue Number:A216030
Chemical Name:AZD-​7648
Synonyms:7,9-Dihydro-7-methyl-2-[(7-methyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(tetrahydro-2H-pyran-4-yl)-8H-purin-8-one;
CAS Number:2230820-11-6
Molecular Formula:C₁₈ H₂₀ N₈ O₂
Molecular Weight:380.4
Category:Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity in non small cell lung cancer.
References:Fok, J. H. L., et al.: Nat. Commun., 10, 1 (2019);
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