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Catalogue Number:A247525
Chemical Name:Adefovir Monopivoxil
Synonyms:Mono-POM Adefovir; Mono(pivaloyloxymethyl) Adefovir; 2,2-Dimethylpropanoic Acid [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]hydroxyphosphinyl]oxy]methyl Ester;
CAS Number:142341-05-7
Molecular Formula:C₁₄H₂₂N₅O₆P
Appearance:White to Light Beige Solid
Melting Point:>137°C (dec.)
Molecular Weight:387.33
Storage:-20°C
Solubility:DMSO (Very Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:The monoester metabolite of the adefovir prodrug Adefovir Dipivoxil (A280465).
References:Shaw, J.-P. et al.: Drug Metab. Dispos., 25, 362 (1997); Annaert, P. et al.: Pharmac. res., 15, 1168 (1998); Annaert, P. et al.: J. Pharmac. Sci., 89, 1054 (2000);
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