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Catalogue Number:A273110
Chemical Name:1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione
Synonyms:M7 Metabolite of Trametinib
CAS Number:1620017-29-9
Molecular Formula:C₂₄H₂₁FIN₅O₄
Molecular Weight:589.4
Category:Building Blocks; Molecular Biology;
Applications:1-(3-Amino-4-hydroxyphenyl)-3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethylpyrido[4,3-d]pyrimidine-2,4,7(1H,3H,6H)-trione may be useful in the synthesis of aminophenyl-dimethyl-iodo-fluoro-phenylamino-cyclopropyl-pyrido-pyrimidine-trione MEK1/2 inhibitors for treating and preventing cancer.
References:Repik, A. E., et al.: PCT Int. Appl., 31pp. (2017)
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