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Catalogue Number:A280465
Chemical Name:Adefovir Dipivoxil
Synonyms:2,2-Dimethyl-propanoic Acid 1,1'-[[[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphinylidene]bis(oxymethylene)] Ester; Hepsera; Preveon; bis(POM)-PMEA;
CAS Number:142340-99-6
Molecular Formula:C₂₀H₃₂N₅O₈P
Appearance:White to Off-White Solid
Melting Point:100-102°C
Molecular Weight:501.47
Storage:4°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI).
References:Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010), Ming, X., et al.: Biochem. Pharmacol., 79, 455 (2010),
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