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Catalogue Number:A282125
Chemical Name:4-​(4-​Amino-​3-​chlorophenoxy)​-​7-​methoxy-6-​quinolinecarboxylic Acid Methyl Ester
Synonyms:Methyl 4-(4-Amino-3-chlorophenoxy)-7-methoxyquinoline-6-carboxylate
CAS Number:417723-07-0
Molecular Formula:C₁₈H₁₅ClN₂O₄
Appearance:Pale Brown to Brown Solid
Melting Point:151 - 153°C
Molecular Weight:358.78
Storage:4°C
Solubility:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Not Determined
Category:Research Tools; Molecular Biology;
Applications:4-​(4-​Amino-​3-​chlorophenoxy)​-​7-​methoxy-6-​quinolinecarboxylic Acid Methyl Ester is an intermediate in the synthesis of Desamino Hydroxy Descyclopropyl Lenvatinib Hydrochloride (D282115) which is a derivative compound of Lenvatinib (L329400), which functions as an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.
References:Matsui, J., et al.: Clin. Cancer Res., 14, 5459 (2008); Gild, M., et al.: Nature Rev. Endocrinol., 7, 617 (2011)
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