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CAS:791828-58-5|Aderbasib

发布时间:2024-06-05 分享至:

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Catalogue Number:A291560
Chemical Name:Aderbasib
Synonyms:(6S,7S)-7-[(Hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylic Acid Methyl Ester; INCB 007839;
CAS Number:791828-58-5
Molecular Formula:C₂₁H₂₈N₄O₅
Molecular Weight:416.47
Category:Research Tools;
Applications:Aderbasib is a azaspiro[2.5]octanehydroxamide derivative as inhibitor of metalloproteases for the treatment of disorders such as cancer, arthritis, cardiovascular or skin disorders.
References:Kuipers, W., et al.: J. Med. Chem., 38, 1942 (1995), Molina, M.A., et al.: Clin. Cancer Res., 8, 347 (2002), Moss, M.L., et al.: Biochemistry, 43, 7227 (2004),
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