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Catalogue Number:A295200
Chemical Name:2-Amino-N-[4-bromo-2-(2-chlorobenzoyl)phenyl]acetamide
CAS Number:86636-70-6
Molecular Formula:C₁₅H₁₂BrClN₂O₂
Molecular Weight:367.62
Category:Building Blocks; Miscellaneous;
Applications:2-Amino-N-[4-bromo-2-(2-chlorobenzoyl)phenyl]acetamide is an intermediate in the synthesis of 3-Hydroxyphenazepam (H949550), a metabolite of Phenazepam (P295300), which is a benzodiazepine drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.
References:Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989); Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993); Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008)
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