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Catalogue Number:A571190
Chemical Name:2-Aminoethyl-amino Palbociclib
Synonyms:6-Acetyl-​2-​[[5-​[(2-​aminoethyl)​amino]​-​2-​pyridinyl]​amino]​-​8-​cyclopentyl-​5-​methyl-pyrido[2,​3-​d]​pyrimidin-​7(8H)​-​one; Palbociclib Impurity; 6-Acetyl-2-[5-(2-aminoethylamino)pyridin-2-ylamino]-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
CAS Number:571191-15-6
Molecular Formula:C₂₂H₂₇N₇O₂
Molecular Weight:421.5
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
Applications:2-Aminoethyl-amino Palbociclib is an impurity of Palbociclib (also known as compound number PD-0332991) (P139900), which is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. 2-Aminoethyl-amino Palbociclib can be used to prepare drugs for treating bacterial infections and breast cancer.
References:Xiang, F., et.al., Faming Zhuanli Shenqing, 38,(2020); Xiang, F., et.al., Faming Zhuanli Shenqing, 17,(2020); Finn, R., et al.: Breast Cancer Res., 11, 5 (2009);
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