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CAS:400602-35-9|Amlodipine Maleate Adduct

发布时间:2024-06-06 分享至:

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Catalogue Number:A575240
Chemical Name:Amlodipine Maleate Adduct
Synonyms:L-Aspartate Amlodipine; Amlodipine Aspartate;4-(2-chlorophenyl)-2-[[2-[(1,2-dicarboxyethyl)amino]ethoxy]methyl]-1,4-dihydro-6-methyl-3,5-Pyridinedicarboxylic acid 3-ethyl 5-methyl ester
CAS Number:400602-35-9
Molecular Formula:C₂₄H₂₉ClN₂O₉
Appearance:White to Off-White Solid
Melting Point:>152°C (dec.)
Molecular Weight:524.95
Storage:-20°C
Solubility:DMF (Slightly), DMSO (Slightly)
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Amlodipine Aspartate, is an impurity of Amlodipine, a dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.
References:Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995),
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