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Catalogue Number:A575505
Chemical Name:Alosetron M5
Synonyms:2,3,4,5-Tetrahydro-2-[[5-(hydroxymethyl)-1H-imidazol-4-yl]methyl]-5-methyl-1H-pyrido[4,3-b]indol-1-one
CAS Number:863485-46-5
Molecular Formula:C₁₇H₁₈N₄O₂
Molecular Weight:310.35
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Alosetron M5 is a derivative of Alosetron (A575500, HCl salt) which is a serotonin 5HT3-receptor antagonist used in treatment of irritable bowel syndrome.
References:Camilleri, M., et al.: Lancet, 355, 1035 (2000); Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002); Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003); Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006); Gleeson, M., et al.: J. Med. Chem., 50, 101 (2007)
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