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CAS:183718-77-6|AM 404

发布时间:2024-06-06 分享至:

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Catalogue Number:A575810
Chemical Name:AM 404
Synonyms:(5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenamide; (all-Z)-N-(4-Hydroxyphenyl)-5,8,11,14-eicosatetraenamide;
CAS Number:183718-77-6
Molecular Formula:C₂₆H₃₇NO₂
Appearance:Pale Orange to Orange Waxy Solid
Molecular Weight:395.58
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Stability
Light Sensitive
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:It is a metabolite of the well-known analgesic Paracetamol. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo.
References:Basile, S., et al.: Pain, 52, 217
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