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CAS:1185244-71-6|AM 404-d4

发布时间:2024-06-06 分享至:

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Catalogue Number:A575812
Chemical Name:AM 404-d4
Synonyms:(5Z,8Z,11Z,14Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide; (all-Z)-N-(4-Hydroxyphenyl-d4)-5,8,11,14-eicosatetraenamide;
CAS Number:1185244-71-6
Alternate CAS #
unlabelled: 183718-77-6
Molecular Formula:C₂₆H₃₃D₄NO₂
Appearance:Pale Brown to Light Brown Solid
Melting Point:48-50°C
Molecular Weight:399.6
Storage:-20°C, Inert atmosphere, Light sensitive
Solubility:Dichloromethane (Slightly), DMSO (Slightly)
Stability
Light Sensitive
Category:Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Lipids/Fatty Acids, Glycerol Derivatives;
Applications:It is a labelled metabolite of the well-known analgesic Paracetamol. AM404 inhibits endocannabinoid cellular uptake, binds weakly to CB1 and CB2 cannabinoid receptors, and is formed by fatty acid amide hydrolase (FAAH) in vivo.
References:Basile, S., et al.: Pain, 52, 217
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