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Catalogue Number:A575863
Chemical Name:Ambrisentan-d10
Synonyms:(αS)-α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-(phenyl-2,3,4,5,6-d5)benzene-2,3,4,5,6-d5-propanoic Acid;
CAS Number:1046116-27-1
Alternate CAS #
Unlabelled: 177036-94-1
Molecular Formula:C₂₂H₁₂D₁₀N₂O₄
Appearance:White to Off-White Solid
Melting Point:>160°C (dec.)
Molecular Weight:388.48
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Very Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ambrisentan-d10, is the labeled analogue of Ambrisentan (A575860), a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.
References:Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),
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