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Catalogue Number:A575875
Chemical Name:Ambenonium Dichloride
Synonyms:N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium Chloride; [Oxalylbis(iminoethylene)]bis[(o-chlorobenzyl)diethylammonium Dichloride (8CI); , N,N'-[(1,2-Dioxo-1,2-ethanediyl)bis(imino-2,1-ethanediyl)]bis[2-chloro-N,N-diethylbenzenemethanaminium Dichloride; [Oxalylbis(iminoethylene)]bis[(o-chlorobenzyl)diethylammonium Chloride]; Ambenonium Chloride; Ambestigmin Chloride; Misuran; Mysuran; Mysuran Chloride; Mytelase; Mytelase Chloride; N,N'-Bis-(2-diethylaminoethyl)oxamide bis-2-chlorobenzylchloride; N,N'-Bis-2-[(2-chlorobenzyl)diethylammonium chloride]-ethyloxamide; Oxamizil; Oxazil; Oxazyl; Win 8077
CAS Number:115-79-7
Alternate CAS #
Free compound: 7648-98-8
Molecular Formula:C₂₈H₄₂Cl₄N₄O₂
Appearance:White to Pale Yellow Solid
Melting Point:198-204°C
Molecular Weight:608.47
Storage:-20°C, Hygroscopic
Solubility:DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Hygroscopic
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Ambenonium Dichloride used in the discovery and design of ApoE4 (apolipoprotein E4) inhibitors with biological activity showing against Alzheimer’s disease. Cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References:Dhanachandra S. et al.: Med. Chem. Res., 21, 825 (2012); Papp, M. et al.: Neurobio. Aging, 27, 402 (2006);
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