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Catalogue Number:A575965
Chemical Name:Alternariol-9-methylether-3-β-D-(4’-malonyl)-glucoside
Synonyms:3-(((2R,3S,4R,5R,6S)-4,5-Dihydroxy-6-((7-hydroxy-9-methoxy-1-methyl-6-oxo-6H-benzo[c]chromen-3-yl)oxy)-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3-oxopropanoic Acid; 3-[[4-O-(2-Carboxyacetyl)-β-D-glucopyranosyl]oxy]-7-hydroxy-9-methoxy-1-methyl-6H-Dibenzo[b,d]pyran-6-one;
CAS Number:1779520-72-7
Molecular Formula:C₂₄H₂₄O₁₃
Molecular Weight:520.44
Category:Standards; Enzyme Activators and Inhibitors; Environmental Standards, Mutagens and Metabolites;
Applications:Alternariol-9-methylether-3-β-D-(4’-malonyl)-glucoside is a metabolite of Alternariol (A575760), a alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing he rate of DNA strand breaks.
References:Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009), Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009), Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009),
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