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Catalogue Number:A576560
Chemical Name:AMG-232
Synonyms:2-((3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic Acid;
CAS Number:1352066-68-2
Molecular Formula:C₂₈H₃₅Cl₂NO₅S
Appearance:White to Off-White Solid
Melting Point:160-164ºC
Molecular Weight:568.55
Storage:-20°C
Solubility:DMSO (Slightly), Methanol (Slightly)
Category:Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:AMG-232 is a potent MDM2-P53 inhibitor for use as an anti-tumor agent.
References:Sun, S. et al.: J Med. Chem., 57, 1454 (2014); Ye, Q. et al.: Xenobiotica, 45, 681 (2015);
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