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Catalogue Number:A576575
Chemical Name:AMG 337
Synonyms:6-[(1R)-1-[8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-1,2,4-triazolo[4,3-a]pyridin-3-yl]ethyl]-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one; Compound M;
CAS Number:1173699-31-4
Molecular Formula:C₂₃H₂₂FN₇O₃
Appearance:Pale Yellow Solid
Molecular Weight:463.46
Storage:4°C, Inert atmosphere
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Research Tools; Molecular Biology; Enzyme Activators and Inhibitors;
Applications:AMG 337 is a potent and selective inhibitor of mesencymal epethelial transition factor (MET factor) which has been implicated in several cancers.
References:Boezio, A. et al.: J. Med. Chem., 59, 2326 (2016);
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