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Catalogue Number:A580055
Chemical Name:Aminoacetonitrile Hydrochloride
Synonyms:2-Amino-acetonitrile Hydrochloride; Amino-acetonitrile Monohydrochloride; Glycinonitrile Monohydrochloride; 2-Aminoacetonitrile Hydrochloride; Aminoacetonitrile Hydrochloride; Aminoacetonitrile Monohydrochloride; Glycinonitrile Hydrochloride; α-Aminoacetonitrile Hydrochloride
CAS Number:6011-14-9
Alternate CAS #
540-61-4 free amine
Molecular Formula:C₂H₅ClN₂
Appearance:White to Off-White Solid
Melting Point:>131°C
Molecular Weight:92.53
Storage:4°C
Solubility:Methanol (Slightly, Heated), Water
Category:Building Blocks; Miscellaneous;
Applications:Aminoacetonitrile is a useful synthetic intermediate. It is a reagent used to synthesize dipeptide nitriles as reversible and potent cathepsin S inhibitors. It can also used to prepare substituted cyclic ureas as possible HIV protease inhibitors.
References:Ward, Y., et al.: J. Med. Chem., 45, 5471 (2002); Wilkerson, W., et al.: J. Med. Chem., 40, 4079 (1997)
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