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Catalogue Number:A580300
Chemical Name:1-Amino-3-adamantanol
Synonyms:3-Amino-1-adamantanol; 3-Aminotricyclo[3.3.1.13,7]decan-1-ol; 1-Amino-3-hydroxyadamantane; (3-Hydroxyadamantan-1-yl)amine;
CAS Number:702-82-9
Molecular Formula:C₁₀H₁₇NO
Appearance:White to Off-White Solid
Melting Point:251-257°C
Molecular Weight:167.25
Storage:4°C
Solubility:DMSO (Sparingly), Methanol (Slightly)
Category:Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:1-Amino-3-adamantanol is a reagent used in the preparation of Vildagliptin. It can also be used in the preparation of quinazolinylureas as TRK kinase inhibitor.
References:Fukushima, H., et al.: Bioorg. Med. Chem., 16, 4093 (2008); Anand, R., et al.: J. Med. Chem., 52, 1602 (2009); Zhao, F., et. al.: Faming Zhuanli Shenqing, 88pp. (2021)
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