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Catalogue Number:A585840
Chemical Name:RP 5264 Hydrochloride
Synonyms:2-​[(1S)​-​1-​[4-​Amino-​3-​[3-​fluoro-​4-​(1-​methylethoxy)​phenyl]​-​1H-​pyrazolo[3,​4-​d]​pyrimidin-​1-​yl]​ethyl]​-​6-​fluoro-​3-​(3-​fluorophenyl)​-4H-​1-​benzopyran-​4-​one Hydrochloride
CAS Number:1532533-78-0
Molecular Formula:C₃₁H₂₄F₃N₅O₃ • HCl
Molecular Weight:571.55 + (36.46)
Category:Research Tools; Miscellaneous; Molecular Biology; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:2-​[(1S)​-​1-​[4-​Amino-​3-​[3-​fluoro-​4-​(1-​methylethoxy)​phenyl]​-​1H-​pyrazolo[3,​4-​d]​pyrimidin-​1-​yl]​ethyl]​-​6-​fluoro-​3-​(3-​fluorophenyl)​-4H-​1-​benzopyran-​4-​one Hydrochloride (1:1) is a drug candidate. It is used in the preparation of 1H-Pyrazolo[3,4-d]pyrimidine derivatives as selective PI3K delta inhibitors for treatment of autoimmune and inflammatory disorders, and proliferative diseases such as cancer.
References:Vakkalanka, S. K. V. S., et al., PCT Int. Appl., 57pp., (2014);
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