货号：E-2024052231
CAS：1146699-66-2
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C379830
Chemical Name:(R)-2-[[4-chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide
Synonyms:(2R)-2-[N-[(4-Chlorophenyl)sulfonyl]-N-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide; Avagacestat; BMS 708163; BMS 708163-01;
CAS Number:1146699-66-2
Molecular Formula:C₂₀H₁₇ClF₄N₄O₄S
Appearance:White Solid
Melting Point:157-160°C
Molecular Weight:520.88
Storage:4°C
Solubility:Chloroform (Slightly), Methanol (Slightly)
Category:Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Avagacestat acts as a γ-secretase inhibitor allowing for treatment of ALzheimer’s disease. On addition it has seen uses targeting embryonic signaling pathways, which control stem cell and cellular development process in cancer therapy.
References:Harris, PJ. et al.: Expert. Opin. Ther. Tar., 16, 131 (2012); Gilman, K.W. et al.: ACS Med. Chem. Lett., 1, 120 (2010);
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