货号：E-2024052360
CAS：4684-94-0
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:C380615
Chemical Name:6-Chloropyridine-2-carboxylic Acid
Synonyms:6-Chloropicolinic Acid; 6-Chloro-2-pyridinecarboxylic Acid; 2-Chloropyridine-6-carboxylic Acid; NSC 51587
CAS Number:4684-94-0
Molecular Formula:C₆H₄ClNO₂
Appearance:White to Pale Yellow Solid
Melting Point:185-189°C
Molecular Weight:157.55
Storage:-20°C
Solubility:DMSO (Slightly), Methanol
Category:Building Blocks; Miscellaneous;
Applications:6-Chloropyridine-2-carboxylic Acid is an intermediate of Sorafenib b(S676850), a multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.
References:Richly, H., et al.: Int. J. Clin. Pharmacol. Ther., 41, 620 (2003); Khire, U.R., et al.: Bioorg. Med. Chem. Lett., 14, 783 (2004); Wilhelm, S.M., et al.: Cancer Res., 64, 7099 (2004); Rini, B.I., et al.: Expert Opin. Pharmacother., 7, 453 (2006)
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