货号：E-2024066609
CAS：130641-38-2
规格：mg(更多包装需求请咨询客服)
纯度：95%+
生产商：试剂家

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Catalogue Number:B387050
Chemical Name:Bindarit
Synonyms:2-Methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]propanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic Acid; 2-[(1-Benzyl-1H-indazol-3-yl)methoxy]-2-methylpropionic Acid; AF 2838;
CAS Number:130641-38-2
Molecular Formula:C₁₉H₂₀N₂O₃
Molecular Weight:324.37
Category:Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications:Bindarit shows anti-inflammatory activity due to a selective inhibition of a subfamily of inflammatory chemokines. Bindarit is a also protein antidenaturant agent. Bindarit modulates the NFkB pathway and has been shown to reduce secondary phase of adjuvant arthritis in rats.
References:Mora, E. et al.: Call Cycle, 11, 169 (2012); Cioli, V. et al.: J. Rheumatol., 19, 1735 (1992); Guglielmotti, A. et al.: Inflam. Res., 51, 252 (2002); Grassia, G. et al.: Cardio. Res., 84, 485 (2009);
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